Study Information

What is recurrent depression?

Depression is often a recurrent disorder. This means that for many people with depression, even after they are treated and get better, depression may return in the future.

This can be a problem for older adults, particularly people who have had several depressive episodes in the past.

We currently do not understand what factors may increase the risk of depression returning, but the Rembrandt study is looking into what possible warning signs may be. We hope that we will be able to better predict who is at the highest risk for depression returning, and how we can develop new treatment options to help keep people happy and healthy.

Am I a good fit for this study?

You may be a good fit for this study if you:

• Are 60 years of age or older
• You are currently depressed or have had your depression improve within the last 4 months
• You are able to have an MRI
• You do not have any mental health problems other than depression and anxiety

What will this study look like for me?

This is the first part in a two-part research study. Over the span of approximately 8-20 weeks, the study will include the following:

• 2-5 visits to our office
• clinical evaluations
• a standardized depression treatment plan in collaboration with your doctor

Participants will receive up to $160 for completing this part of the study. If your depression responds to treatment, you then enter a second study phase.

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